FIGURE 1: Level of intellectual disability

  Level of intellectual disability
  Normal Borderline Mild Moderate Severe Profound
Syndrome            
Angelman         * *
Cockayne Intellectual disability is progressive
Coffin-Lowry Females only Males only
Coffin-Siris     * * *  
Cornelia de Lange       * *  
Cri du chat         *  
Crouzon     * *    
Down's     * *    
Duchenne muscular dystrophy * * *      
Fragile-X     * *    
Galactosaemia   *        
Kallman * *        
Lesch-Nyhan     * *    
Lowe       * *  
Mucopolysaccharidoses     * * *  
Myonic dystrophy     * *    
Neurofibromatosis type 1   *        
Noonan * * *      
Phenylketonuria (1)       * *  
Prader-Willi   * * * *  
Rett           *
Rubenstein-Taybi     * * *  
Smith-Lemli-Opitz   * * * * *
Smith-Megenis       *    
Sex aneuploidies:  
- Klinefelter * *        
- Turner * *        
Sotos   * *      
Tuberous sclerosis * * * * * *
Velocardiofacial   *        
Williams       *    
Wolf-Hirschhorn         * *

(1) If left untreated